- Region
- Águilas
- Alhama de Murcia
- Jumilla
- Lorca
- Los Alcázares
- Mazarrón
- San Javier
-
ALL AREAS & TOWNS
- AREAS
- SOUTH WEST
- MAR MENOR
- MURCIA CITY & CENTRAL
- NORTH & NORTH WEST
- TOWNS
- Abanilla
- Abarán
- Aguilas
- Alamillo
- Alcantarilla
- Aledo
- Alhama de Murcia
- Archena
- Balsicas
- Blanca
- Bolnuevo
- Bullas
- Cañadas del Romero
- Cabo de Palos
- Calasparra
- Camping Bolnuevo
- Campo De Ricote
- Camposol
- Canada De La Lena
- Caravaca de la Cruz
- Cartagena
- Cehegin
- Ceuti
- Cieza
- Condado de Alhama
- Corvera
- Costa Cálida
- Cuevas De Almanzora
- Cuevas de Reyllo
- El Carmoli
- El Mojon
- El Molino (Puerto Lumbreras)
- El Pareton / Cantareros
- El Raso
- El Valle Golf Resort
- Fortuna
- Fuente Alamo
- Hacienda del Alamo Golf Resort
- Hacienda Riquelme Golf Resort
- Isla Plana
- Islas Menores & Mar de Cristal
- Jumilla
- La Azohia
- La Charca
- La Manga Club
- La Manga del Mar Menor
- La Pinilla
- La Puebla
- La Torre
- La Torre Golf Resort
- La Unión
- Las Palas
- Las Ramblas
- Las Ramblas Golf
- Las Torres de Cotillas
- Leiva
- Librilla
- Lo Pagan
- Lo Santiago
- Lorca
- Lorquí
- Los Alcázares
- Los Balcones
- Los Belones
- Los Canovas
- Los Nietos
- Los Perez (Tallante)
- Los Urrutias
- Los Ventorrillos
- Mar De Cristal
- Mar Menor
- Mar Menor Golf Resort
- Mazarrón
- Mazarrón Country Club
- Molina de Segura
- Moratalla
- Mula
- Murcia City
- Murcia Property
- Pareton
- Peraleja Golf Resort
- Perin
- Pilar de la Horadada
- Pinar de Campoverde
- Pinoso
- Playa Honda
- Playa Honda / Playa Paraíso
- Pliego
- Portmán
- Pozo Estrecho
- Puerto de Mazarrón
- Puerto Lumbreras
- Puntas De Calnegre
- Region of Murcia
- Ricote
- Roda Golf Resort
- Roldan
- Roldan and Lo Ferro
- San Javier
- San Pedro del Pinatar
- Santiago de la Ribera
- Sierra Espuña
- Sucina
- Tallante
- Terrazas de la Torre Golf Resort
- Torre Pacheco
- Totana
- What's On Weekly Bulletin
- Yecla
- EDITIONS: Spanish News Today Alicante Today Andalucia Today
ARCHIVED - First clinical trial of Covid vaccine in Spain gets underway in Madrid
The Janssen trials involve two hospitals in Madrid and one in Santander
On Tuesday the vaccination of 150 volunteer participants in the phase 2 clinical trial of the first vaccine against Covid-19 to be trialled in Spain, made by pharmaceutical company Janssen, began in Madrid.
The Madrid hospitals of La Paz and La Princesa are, together with the Hospital Marqués de Valdecilla in Santander, the three centers participating in this clinical trial, which seeks to find the most appropriate dose and regimen to achieve the best antibody response. This trial, authorized on August 28th by the Spanish Agency for Medicines and Health Products, will analyze a vaccine at an early stage, which is not usual in Spain, but the need to urgently find a protective vaccine against Covid-19 is felt to outweigh the potential risks.
The 150 Madrid volunteers have been spilt into two groups,75 per hospital, 100 between 18 and 55 years old and 50 over 65 years, who will carry out the vaccination trials in the Clinical Trials Units up until September 22nd.
The phase 2 clinical trial will last between 14 and 16 months in total.
It is an early phase of the research, in which it is intended to evaluate which is the most appropriate dose and schedule in terms of activity to achieve the best antibody response (those that generate immunity against the virus), as well as to continue evaluating safety of the product under investigation.
Subsequently, phase 3, multicenter and multinational clinical trials will be necessary to demonstrate that the selected dose is safe and effective in preventing coronavirus infection.
The volunteers in whom the vaccine will be tested must be healthy people, without disease or undertaking any form of existing medical treatment, except in the group over 65s in which some type of mild disease that does not interfere with the possible results is permitted . Volunteers must not have had contact with people who are sick with Covid-19 or have had the virus themselves.
This is a randomized clinical trial in which different branches of treatment will be analyzed. In all cases, two vaccinations will be carried out in each patient, so that some patients will only receive a placebo, others one dose and others two doses of the product under investigation.
Furthermore, it is a double-blind trial in order to prevent that the results may be influenced by the placebo effect or by observer bias.
The follow-up of the patients will be carried out through several visits to the center, from the initial screening. After a first vaccination, a diary is given to the participants where they must note any adverse effects and the temperature recorded daily and go to the center weekly for the pertinent controls. After the second dose, visits as well as control calls and safety analyzes will be carried out.
The La Paz and La Princesa hospitals have modern Clinical Trial Units attached to their Health Research Institutes (IdiPAZ and IIS Princesa), accredited by the competent authorities with extensive experience in conducting clinical trials in healthy volunteers and patients.
In both cases, they strictly comply with the standards of Good Clinical Practice, ensuring the safety of the participants in the different studies at all times.
One in 7 volunteers of the Russian Sputnik V vaccine report side effects
The Moscow Times reported on Tuesday that one in seven volunteers have complained of side effects including weakness and muscle pain after taking Russia’s coronavirus vaccine, Russia’s health minister said on Tuesday.
Final clinical trials of the Sputnik V vaccine began in Moscow earlier this month amid questions over its long-term safety and effectiveness. Health Minister Mikhail Murashko said more than 300 out of the announced 40,000 volunteers have been vaccinated so far, according to the state-run TASS news agency.
“Approximately 14% have small complaints of weakness, muscle pain for 24 hours and an occasional increase in body temperature,” TASS quoted Murashko as saying.
Murashko said the symptoms “level off” by the next day.
“The complications are described in the instructions and are predictable,” he said.
Clinical trials resume of Oxford vaccine
On Saturday Oxford University reported that it will resume clinical trials of the Covid-19 vaccine, called ChAdOx1 nCoV-19, following an interruptionon the 6th September when a volunteer in the United Kingdom suffered an adverse reaction.
This possible vaccine, considered one of the most advanced developed worldwide, is in the final stages of clinical trials before receiving authorization from regulatory bodies to proceed with immunizing the population.
At the end of August, the EU closed a "first contract" with the British pharmaceutical company AstraZeneca guaranteeing access to 300 million doses of the vaccine, so the suspension of the trials was a serious cause for concern in Europe and in all the world. Spain has pre-ordered 3 million doses.
-->